Fellowship Start Year
2021
Status
Continuing
Marco Carpenter
Bio
I am on a mission to understand how environmental factors affect the origins of disease via epigenetic modifications. This work is informed by my background in targeted epigenetic editing. My dissertation research was conducted in the lab of Elizabeth Heller, Ph.D., at the University of Pennsylvania, where I pioneered CRISPR-based approaches for in vivo validation of preclinical drug targets. My dissertation identified both a new target and a new therapeutic concept – druggable transcription factors – as treatment modalities for brain disorders. Currently, I am in the lab of William Peranteau, MD, where I am developing CRISPR-based screens to identify novel transcriptional regulators important for the treatment of pediatric blood disorders.
Postdoc Appointment
Department
- Pediatrics
Center, Lab, or Institute
- Thoracic and Fetal Surgery
Penn Faculty Mentor
- William Peranteau, Ph.D.
Education
Degrees
- 2021, Ph.D., Pharmacology, The University of Pennsylvania, Perelman School of Medicine
- 2014, B.S., Psychology/Neuroscience, Clark University
Disertation Title
Targeting Endogenous Homeostatic Mechanisms for the Treatment of Cocaine Use Disorder: Contribution of NR4A1 and Target Gene Expression
Research Advisors
- Elizabeth A. Heller, Ph.D.